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Uncertainties about stopping or reducing antipsychotics as shared by families

Amelia Talbot considers a qualitative study that explores family members’ perspectives on reducing or discontinuing antipsychotic medication. The post Uncertainties about stopping or reducing...

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Optimal antipsychotic dosing in first-episode schizophrenia: how much is too...

Joe Pierre reports on the first published study exploring the relationship between antipsychotic dose and risk of relapse in first episode schizophrenia, which suggests that standard antipsychotic...

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Predicting treatment-resistant psychosis using routine clinical measures

Lorna Staines summarises a recent study on predicting treatment-resistant psychosis, which suggests that future risk prediction efforts should seek to consider routinely collected data. The post...

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Antipsychotics and risk of violence and suicide in people diagnosed with...

A group of MSc students from UCL summarise a study examining the links between antipsychotics, risk of violent crimes and suicidal behaviour in people diagnosed with a 'personality disorder'. The post...

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Cognition and heterogeneity in First-Episode Psychosis before antipsychotic...

Ana Veic looks at an updated systematic review which suggests that patients with psychosis display cognitive difficulties very early in the disease process, and concludes this variation in cognitive...

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Psychotropic medication during pregnancy: new umbrella review finds no...

Flo Martin summarises a recent umbrella review which finds that we still have limited knowledge about the safety of psychotropic drug use in pregnancy. The post Psychotropic medication during...

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The role of the gut microbiome in treatment-resistant schizophrenia

Nuala Murray explores a recent Australian case-control study that looks at the associations between changes in gut microbiota and schizophrenia diagnosis, treatment resistance, and clozapine response....

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Continuing antipsychotic medication during pregnancy associated with reduced...

Shuichi Suetani and Sarah Thomas highlight new research from Korea which suggests that antipsychotic medications do seem to help reduce the relapse of schizophrenia in pregnant women. The post...

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Quetiapine may pip lithium to the post for augmentation in ‘treatment...

Kirsten Lawson and Douglas Badenoch review the new randomised controlled trial by Cleare et al, published today in The Lancet Psychiatry, directly comparing the clinical and cost effectiveness of...

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Lithium is best at decreasing the risk of depression-related hospitalisation...

This Swedish cohort study, blogged by Duncan Swiffen, is yet more evidence for lithium as an excellent treatment for people with bipolar disorder. This time it comes out on top in terms of preventing...

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