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To stay on antipsychotics or not to stay on antipsychotics? A longstanding...

Joe Pierre considers a recent network meta-analysis on continuing, reducing, switching, or stopping antipsychotics in individuals with schizophrenia-spectrum disorders who are clinically stable. The...

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Do different groups of people with schizophrenia respond differently to...

Murtada Alsaif considers a systematic review and meta-analysis published in the Lancet Psychiatry exploring the response of different subgroups of patients with schizophrenia to different antipsychotic...

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Uncertainties about stopping or reducing antipsychotics as shared by families

Amelia Talbot considers a qualitative study that explores family members’ perspectives on reducing or discontinuing antipsychotic medication. The post Uncertainties about stopping or reducing...

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Optimal antipsychotic dosing in first-episode schizophrenia: how much is too...

Joe Pierre reports on the first published study exploring the relationship between antipsychotic dose and risk of relapse in first episode schizophrenia, which suggests that standard antipsychotic...

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Predicting treatment-resistant psychosis using routine clinical measures

Lorna Staines summarises a recent study on predicting treatment-resistant psychosis, which suggests that future risk prediction efforts should seek to consider routinely collected data. The post...

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Antipsychotics and risk of violence and suicide in people diagnosed with...

A group of MSc students from UCL summarise a study examining the links between antipsychotics, risk of violent crimes and suicidal behaviour in people diagnosed with a 'personality disorder'. The post...

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Cognition and heterogeneity in First-Episode Psychosis before antipsychotic...

Ana Veic looks at an updated systematic review which suggests that patients with psychosis display cognitive difficulties very early in the disease process, and concludes this variation in cognitive...

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Psychotropic medication during pregnancy: new umbrella review finds no...

Flo Martin summarises a recent umbrella review which finds that we still have limited knowledge about the safety of psychotropic drug use in pregnancy. The post Psychotropic medication during...

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The role of the gut microbiome in treatment-resistant schizophrenia

Nuala Murray explores a recent Australian case-control study that looks at the associations between changes in gut microbiota and schizophrenia diagnosis, treatment resistance, and clozapine response....

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